Microscale
Enablers
More
advanced artificial retinas are relying on miniaturized electronics
for processing incoming images and activating the corresponding
electrodes to communicate with retinal cells and ultimately the
brain. The goal of these devices, being developed through a U.S.
Department of Energy (DOE) collaboration, is to continually improve
their visual resolution so that implanted individuals eventually
will be able to read large print, recognize faces, and move about
without aid. Sandia National Laboratories’ expertise in
the development, fabrication, and production of microsystems is
helping to make this goal a reality.
The
Challenge
Biocompatible electronics packages currently used in medical devices
require only a small number of electrical interfaces to operate
them. For example, pacemakers at most have four electrical contacts,
and cochlear implants for the hearing impaired use 22 or fewer.
Additionally, the volume of these packages is typically more than
5 cm3. By comparison, DOE’s artificial retina requires a
much smaller electronics package but one to two orders of magnitude
more electrical feed-throughs to communicate with retinal cells.
This density
is beyond conventional packaging technology. The compact size
of the artificial retina’s electronics package makes it
difficult to mechanically and electrically interconnect the microelectronics
inside. The package also has to withstand the human eye’s
harsh saline environment for the lifetime of the patient, so the
electronics have to be hermetically sealed, preventing all transfer
of moisture and gases between the components inside the package
and the human body.
“Essentially,
we’re trying to cram more and more things into smaller and
smaller spaces,” says Kurt Wessendorf, an analog circuit
designer and leader of Sandia’s artificial retina efforts.
If more electrodes, and hence more capabilities, can be packed
into the system, the images that implanted individuals see will
be of higher resolution. This is the area benefitted by Sandia’s
expertise in microsystems.
Engineering
Tiny Machines
Microsystem devices smaller than a human hair are built on silicon
wafers or chips. They contain electrical circuitry and microelectromechanical
systems (MEMS), which are miniature machines.
The artificial retina’s custom-designed
integrated circuit (IC) is the system’s brain. Its job is
to take signals from the external camera and convert them into
stimuli that are transferred to the electrode array. The IC performs
this function via a series of interconnected, nanosize nodes,
whose locations on the chip’s surface are important because
they can minimize the wire length along which the signal travels
(see figure 1 above).
|
| Figure
2. Three-dimensional model and cross section of a dual-sided
integrated circuit. The circuit enables high-density interconnects
on both top and bottom surfaces. Click on image to enlarge. |
“The current method for achieving higher
electrode currents involves assembly with a lot of bond wires
and other interconnects,” says Sean Pearson, an IC design
engineer at Sandia. “This makes the device tedious to build
and very difficult to yield full functionality.” Consequently,
he and his colleagues are developing a novel, dual-sided IC to
simplify how data are routed and to better integrate the electronics
package with the electrode array (see figure 2 above). “We’re
using one side to bring the signals in and the other side to put
them out,” Pearson explains.
For the electronics substrate, the researchers
are using a Sandia-patented MEMS technique to selectively etch
away parts of the silicon chip or add new structural layers to
create tiny features that cannot be made any other way. This micromachining
process allows wiring of the electrical connections through the
chip for access to both sides.
“By using that bottom surface, which adds
interconnect space instead of eliminating it, we’re able
to get higher interconnect densities,” thereby allowing
the number of electrodes on the array to be increased without
making the device bigger, says Murat Okandan, a microsystems engineer
on the Sandia team.
|
| Figure
3. High-density hermetic electronics packaging with a dual-sided
electronic circuit. Click on image to enlarge. |
Additionally, Sandia researchers are developing
state-of-the-art packaging technologies to assemble and integrate
the microelectronic components with the thin-film electrode array.
Biocompatibility issues are driving much of this effort, requiring
the high-density interconnects to be insulated with a nonconductive
film to prevent moisture and ionic and biological contamination
from causing device failure (see figure 3).
Dual-Use Technology
Sandia has a long history of pioneering microelectronics research,
which feeds into several defense-related systems, including sensor
technologies and satellite applications. Spinoffs of the Artificial
Retina Project—such as the silicon interconnect and higher-density
packaging of components—are being evaluated for potential
applications in some of these ongoing projects.
“The kind of exposure seen in the eye is
not unlike the harsh, corrosive environments in which many defense-related
components are required to survive for many years,” Wessendorf
says. Moreover, “We’re always looking at miniaturizing
and increasing function, and these efforts will help in those
directions.”
Sandia National Laboratories is operated by Sandia
Corporation, a Lockheed Martin company, for the U.S. Department
of Energy’s National Nuclear Security Administration.